Cardiobacterium hominis is a slow-growing, fastidious, capnophilic, Gram- negative bacillus represented by the “C” in HACEK, an acronym for. Cardiobacterium hominis is a member of the HACEK group (Haemophilus paraphrophilus, Haemophilus parainfluenzae, Aggregatibacter. Cardiobacterium hominis, a microaerophilic, pleomorphic gram-negative bacillus , is one of the AACEK organisms. C. hominis is a component of the normal flora.
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Guidelines for antibiotic prophylaxis for GI endoscopy. However, pulmonary valve involvement has been documented To these should be added a single case due to Suttonella indologenes formerly Kingella indologenes Fifty patients had murmurs.
Unlike HaemophilusActinobacillusand Kingella species, it rarely occurs in children one case [ 68 ]. A more profound degree of leukocytosis has been infrequently described in cases where homibis patient was acutely ill on presentation 2. The patient’s troponin I value was slightly increased at 0. At that time, antibiotic treatment was changed to cefotaxime. Cardiobacterium hominis endocarditis manifesting as bacterial meningitis.
Cardiiobacterium Med Microbiol ;3: Between 10 7 and 10 8 viable organisms were injected intravenously, intraperitoneally or subcutaneously into mice, guinea pigs, rabbits, hamsters and pigeons, but produced no evidence of infection Successful treatment with partial resection of the posterior mitral valve leaflet and antibiotic therapy with cefazolin.
However, reports of beta-lactamase-producing C hominis have appeared in the literature over the past decade. The recommended dose of ceftriaxone crdiobacterium 2g once daily intravenously or intramuscularly.
Cardiobacterium hominis endocarditis: two cases and a review of the literature
Notably, all 22 isolates tested against penicillin were susceptible; however, one isolate developed resistance to ampicillin during treatment Subacute infectious endocarditis caused by Cardiobacterium hominis. An electrocardiogram demonstrated sinus tachycardia. Cardiobacterium hominis on blood agar plate.
Rev Infect Dis ;5: The assay used was one described in measuring the antibody response to C. Characterization of the unusual organisms and review of the literature. Cultures of both valves were cardiobacteium for bacteria, acid-fast bacilli and fungi.
Andrew HominiisMD. Mycotic aneurysm formation cerebral, femoral and visceral has also been described 1151644 Physical findings that have been documented in case reports include splinter hemorrhages in Purchase access Subscribe to the journal.
Currently, third-generation cephalosporins such as ceftriaxone are recommended as first-line therapy. Hematuria and a rising creatinine level may suggest the development of this complication Acknowledgments The author wishes to thank Dr F Aoki for his review of the manuscript.
Determination of the antimicrobial activity of 29 clinically important compounds tested against fastidious HACEK cardiobactdrium organisms. Am J Med Sci. As in the prevention of any endocarditis due to normal oral flora, prevention entails good dental hygiene.
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Homihis caused by Kingella indologenes. The patient was discharged home after 22 days in hospital and continued therapy with intravenous antibiotics to complete a four-week course. See other articles in PMC that cite the published article. Identification of Cardiobacterium hominis by broad-range bacterial polymerase chain reaction analysis in cardiobactfrium case of culture-negative endocarditis.
A review of cases from the University of Washington Hospitals, The organism grows well on standard enriched media blood, chocolate, trypticase soy, and Mueller—Hinton agarsbut not on selective enteric media MacConkey agar, eosin methylene blue agar.
Numbers in parentheses indicate the numbers of patients that could be evaluated; where no parentheses appear, percentages reflect those of the total number of cases in a series. Successful treatment with partial resection of czrdiobacterium posterior mitral valve leaflet and antibiotic therapy with cefazolin. All these organisms have the propensity to cause endocarditis, but in the case of C.
Symptoms of heart failure may develop or progress despite appropriate antibiotic therapy depending on the extent of valvular damage before diagnosis Peripheral stigmata of endocarditis were not observed, with the exception of mild splenomegaly. This page was last edited on 15 Novemberat In one study, C.
Acta Pathol Microbiol Scand B. Infectious endocarditis caused by Cardiobacterium hominis.
Cardiobacterium hominis – Wikipedia
Cardiobacterium hominis prosthetic valve endocarditis diagnosed in Portugal [Letter]. It should, however, be noted that the fluoroquinolones have variable activity e. No portion of this site may be reproduced. Printable Version of Antimicrobial Therapy for Cardiobacterium hominis.
Twenty-six days after colonoscopy, trans-esophageal echocardiography TEE revealed vegetations on the prosthetic aortic valve. Botha P, Venter M. She continued to do well 5 months after completion of antibiotic therapy.