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Date: September 9, 2019 Author: admin Comments: 0
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ANEMILERIN SNFLANDRLMAS PDF

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Tedavisiz anemilerun hzl, fatal seyreder. Yumuak doku plazmositomlar en sk akcierler, sinsler, larinks ve nazofarinkste yerleir. Erken evrelerde 10 yl olabilir. En sk gelitii ekstranodal doku mide dir. Afrikada endemik olduu yerlerde tm vakalar EBV ile ilikilidir. Ancak kapsl dna yaylm, lokal invazyon yapabilir. Byk hacimli IgM kan akmn yavalatr; hiperviskosite sendromuna neden olur.

Alveoler kapillerlerde mikrotrombsler, pulmoner dem, fibrin eksdasyonu, hiyalen membranlar. Duyu ve motor bozukluklarn birlikte olmas subakut kombine dejenerasyon veya kombine sistem hastal olarak adlandrlr. Mikrobik ajanlar Hcresel debris Dolama karan yabanc maddeler Nekrotik dokular Lenf dmleri imi ve arl olup bazen zerindeki deride kzarklk vardr. Neoplastik Langerhans hcre infiltrasyonu nedeni ile deri lezyonlar belirgindir, seboreik erpsiyonlar oluur.

Sistemik yaylmlarn olduka ge yaparlar. Genler ve ocuklar etkiler, kemiklerde multifokal eroziv kitleler oluur.

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HEMATOPOETiK SiSTEM (Patoloji – Davut Sahin)

Postpartum Sheehan sendromu hipofiz nekrozu. Kavernz snflandrlmaw tmr deil hamartomdur. Lsemi ve lenfomalar malign tmrlerdir. En sk kafa kemikleri, kostalar ve femur etkilenir. P gastriti, Sjgren sendromu, Hashimoto tiroiditi, kronik enterit ve kolit, bronlarakcier ve nonmukozal dokulardan tkrk bezi, meme, tiroid, orbita kaynaklanr.

En sk konjenital aplastik anemi sebebidir.

Genellikle 2 ya ncesi oluur. Gvdenin n ve arka yz ile skalp belirgin olarak etkilenir.

HEMATOPOETiK SiSTEM (Patoloji – Davut Sahin)

Membrana yakn adet veya 1 adet santral nkleolldr. Anormal eritroid ve miyeloid ncllerin kemik iliinde otohemolize uramas pansitopeniye yol aar. Reed-Sternberg hcresine bezer ekilde olabilir.

Demir depolar hemosiderin, ferritin azalr.

Follikl merkezindeki kk veya byk entikli hcrelerden oluur ve morfolojileri bu hcrelere benzer. Mukozal dokular mide H. Hematopoetik Sistem, mmnoloji, Mikrobiyoloji Documents. Ntrofillerde irileme makropolimorfonkleer ve hipersegmentasyonSantral Sinir Sistemi Deiiklikleri: Zeminde reaktif hcreler son derece az.

anemilerinn

Ar eritrosit yapm, ilikte ar genileme Kemik deformiteleri crew haircut asker tra Periferik dolamda retiklositoz ve normoblastlar grlr. Sporadik grld yerlerde barsak ileoekal blgeretroperiton, overler tutulur. Histolojisi benign amemilerin ile ayndr.

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Ar, hassasiyet, patolojik krk yapabilir. Tm Dnyada en sk grlen anemi trdr.

Soliter kemik miyelomu, MM ile ayn yerlerde yerleir. Tipik olarak ocukluk anda Nadiren boyun, tiroid, pulmoner anmeilerin ve dier yerlerde olur. Tmr hcreleri normal lenfositin kat aptadr. Kemiklerde litik lezyonlar olmaz. Deri bulgusu olarak generalize eksoliyatif eritroderma tablosu oluur.

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